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Mining statistically-solid k-mers for accurate NGS error correction

BACKGROUND: NGS data contains many machine-induced errors. The most advanced methods for the error correction heavily depend on the selection of solid k-mers. A solid k-mer is a k-mer frequently occurring in NGS reads. The other k-mers are called weak k-mers. A solid k-mer does not likely contain er...

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Detalles Bibliográficos
Autores principales: Zhao, Liang, Xie, Jin, Bai, Lin, Chen, Wen, Wang, Mingju, Zhang, Zhonglei, Wang, Yiqi, Zhao, Zhe, Li, Jinyan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6311904/
https://www.ncbi.nlm.nih.gov/pubmed/30598110
http://dx.doi.org/10.1186/s12864-018-5272-y