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Identification of cancer subtypes from single-cell RNA-seq data using a consensus clustering method
BACKGROUND: Human cancers are complex ecosystems composed of cells with distinct molecular signatures. Such intratumoral heterogeneity poses a major challenge to cancer diagnosis and treatment. Recent advancements of single-cell techniques such as scRNA-seq have brought unprecedented insights into c...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6311928/ https://www.ncbi.nlm.nih.gov/pubmed/30598115 http://dx.doi.org/10.1186/s12920-018-0433-z |