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Constructing tissue-specific transcriptional regulatory networks via a Markov random field

BACKGROUND: Recent advances in sequencing technologies have enabled parallel assays of chromatin accessibility and gene expression for major human cell lines. Such innovation provides a great opportunity to decode phenotypic consequences of genetic variation via the construction of predictive gene r...

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Detalles Bibliográficos
Autores principales: Ma, Shining, Jiang, Tao, Jiang, Rui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6311931/
https://www.ncbi.nlm.nih.gov/pubmed/30598101
http://dx.doi.org/10.1186/s12864-018-5277-6