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In silico design of MHC class I high binding affinity peptides through motifs activation map

BACKGROUND: Finding peptides with high binding affinity to Class I major histocompatibility complex (MHC-I) attracts intensive research, and it serves a crucial part of developing a better vaccine for precision medicine. Traditional methods cost highly for designing such peptides. The advancement of...

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Detalles Bibliográficos
Autores principales: Xiao, Zhoujian, Zhang, Yuwei, Yu, Runsheng, Chen, Yin, Jiang, Xiaosen, Wang, Ziwei, Li, Shuaicheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6311935/
https://www.ncbi.nlm.nih.gov/pubmed/30598069
http://dx.doi.org/10.1186/s12859-018-2517-3