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Novel disease syndromes unveiled by integrative multiscale network analysis of diseases sharing molecular effectors and comorbidities

BACKGROUND: Forty-two percent of patients experience disease comorbidity, contributing substantially to mortality rates and increased healthcare costs. Yet, the possibility of underlying shared mechanisms for diseases remains not well established, and few studies have confirmed their molecular predi...

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Detalles Bibliográficos
Autores principales: Li, Haiquan, Fan, Jungwei, Vitali, Francesca, Berghout, Joanne, Aberasturi, Dillon, Li, Jianrong, Wilson, Liam, Chiu, Wesley, Pumarejo, Minsu, Han, Jiali, Kenost, Colleen, Koripella, Pradeep C., Pouladi, Nima, Billheimer, Dean, Bedrick, Edward J., Lussier, Yves A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6311938/
https://www.ncbi.nlm.nih.gov/pubmed/30598089
http://dx.doi.org/10.1186/s12920-018-0428-9