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A seven-Gene Signature assay improves prognostic risk stratification of perioperative chemotherapy treated gastroesophageal cancer patients from the MAGIC trial

BACKGROUND: Following neoadjuvant chemotherapy for operable gastroesophageal cancer, lymph node metastasis is the only validated prognostic variable; however, within lymph node groups there is still heterogeneity with risk of relapse. We hypothesized that gene profiles from neoadjuvant chemotherapy...

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Detalles Bibliográficos
Autores principales: Smyth, E C, Nyamundanda, G, Cunningham, D, Fontana, E, Ragulan, C, Tan, I B, Lin, S J, Wotherspoon, A, Nankivell, M, Fassan, M, Lampis, A, Hahne, J C, Davies, A R, Lagergren, J, Gossage, J A, Maisey, N, Green, M, Zylstra, J L, Allum, W H, Langley, R E, Tan, P, Valeri, N, Sadanandam, A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6311954/
https://www.ncbi.nlm.nih.gov/pubmed/30481267
http://dx.doi.org/10.1093/annonc/mdy407