Vascular endothelial cell expression of JAK2(V617F) is sufficient to promote a pro-thrombotic state due to increased P-selectin expression

Thrombosis is the main cause of morbidity and mortality in patients with JAK2(V617F) myeloproliferative neoplasms. Recent studies have reported the presence of JAK2(V617F) in endothelial cells of some patients with myeloproliferative neoplasms. We investigated the role of endothelial cells that expr...

Descripción completa

Detalles Bibliográficos
Autores principales: Guy, Alexandre, Gourdou-Latyszenok, Virginie, Le Lay, Nicolas, Peghaire, Claire, Kilani, Badr, Dias, Juliana Vieira, Duplaa, Cécile, Renault, Marie-Ange, Denis, Cécile, Villeval, Jean Luc, Boulaftali, Yacine, Jandrot-Perrus, Martine, Couffinhal, Thierry, James, Chloe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ferrata Storti Foundation 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6312008/
https://www.ncbi.nlm.nih.gov/pubmed/30171023
http://dx.doi.org/10.3324/haematol.2018.195321

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6312008/
https://www.ncbi.nlm.nih.gov/pubmed/30171023
http://dx.doi.org/10.3324/haematol.2018.195321

Ejemplares similares