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Evodiamine inactivates NF-κB and potentiates the antitumor effects of gemcitabine on tongue cancer both in vitro and in vivo

OBJECTIVE: The aim of this study was to investigate whether evodiamine (EVO) could potentiate the antitumor activity of gemcitabine (GEM) in tongue cancer cells and determine its potential underlying mechanisms. MATERIALS AND METHODS: Human Tca8113 and CAL-27 tongue squamous carcinoma cell lines wer...

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Detalles Bibliográficos
Autores principales: Guo, Qi, Liu, Yanmei, Zhao, Jiayuan, Wang, Jing, Li, Yue, Pang, Yunqing, Chen, Jian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6312051/
https://www.ncbi.nlm.nih.gov/pubmed/30643424
http://dx.doi.org/10.2147/OTT.S181062