Cargando…

Evodiamine inactivates NF-κB and potentiates the antitumor effects of gemcitabine on tongue cancer both in vitro and in vivo

OBJECTIVE: The aim of this study was to investigate whether evodiamine (EVO) could potentiate the antitumor activity of gemcitabine (GEM) in tongue cancer cells and determine its potential underlying mechanisms. MATERIALS AND METHODS: Human Tca8113 and CAL-27 tongue squamous carcinoma cell lines wer...

Descripción completa

Detalles Bibliográficos
Autores principales:	Guo, Qi, Liu, Yanmei, Zhao, Jiayuan, Wang, Jing, Li, Yue, Pang, Yunqing, Chen, Jian
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove Medical Press 2018
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6312051/ https://www.ncbi.nlm.nih.gov/pubmed/30643424 http://dx.doi.org/10.2147/OTT.S181062

Ejemplares similares

Gene regulation analysis of the effects of evodiamine on tongue squamous cell carcinoma
por: Wu, Yuyan, et al.
Publicado: (2019)

Inhibitory effects of evodiamine on zymosan-induced inflammation: inactivation of NF-κB by inhibiting IκBα phosphorylation
por: Fan, X, et al.
Publicado: (2014)

Enhanced Antitumor Efficacy of Gemcitabine by Evodiamine on Pancreatic Cancer via Regulating PI3K/Akt Pathway
por: Wei, Wei-Tian, et al.
Publicado: (2011)

Evaluation of the Cardiotoxicity of Evodiamine In Vitro and In Vivo
por: Yang, Weifeng, et al.
Publicado: (2017)

Antitumor Effects of Evodiamine in Mice Model Experiments: A Systematic Review and Meta-Analysis
por: Yin, Cong, et al.
Publicado: (2021)

Sensitizing leukemia stem cells to NF-κB inhibitor treatment in vivo by inactivation of both TNF and IL-1 signaling
por: Li, Jing, et al.
Publicado: (2016)

Evodiamine protects against airway remodelling and inflammation in asthmatic rats by modulating the HMGB1/NF-κB/TLR-4 signalling pathway
por: Wang, Qiong, et al.
Publicado: (2021)

Effect of Evodiamine on Collagen-Induced Platelet Activation and Thrombosis
por: Yang, Xiaona, et al.
Publicado: (2022)

Protective Effects of Evodiamine against LPS-Induced Acute Kidney Injury through Regulation of ROS-NF-κB-Mediated Inflammation
por: Shi, Yan, et al.
Publicado: (2019)

The Protective Effect of Evodiamine in Osteoarthritis: An In Vitro and In Vivo Study in Mice Model
por: Xian, Shuyuan, et al.
Publicado: (2022)

Evodiamine alleviates severe pneumonia induced by methicillin-susceptible Staphylococcus aureus following cytomegalovirus reactivation through suppressing NF-κB and MAPKs
por: Chen, Xin, et al.
Publicado: (2018)

Evodiamine reduced peripheral hypersensitivity on the mouse with nerve injury or inflammation
por: Zhang, Wen-Dong, et al.
Publicado: (2020)

Evodiamine as the Active Compound of Evodiae fructus to Inhibit Proliferation and Migration of Prostate Cancer through PI3K/AKT/NF-κB Signaling Pathway
por: Lei, Yuhe, et al.
Publicado: (2022)

Antitumor activity of gemcitabine against high-grade meningioma in vitro and in vivo
por: Takeda, Hiroyuki, et al.
Publicado: (2017)

Huaier increases the antitumor effect of gemcitabine on pancreatic cancer in vitro and in vivo
por: Chen, Tao, et al.
Publicado: (2021)

Evodiamine and Rutaecarpine as Potential Anticancer Compounds: A Combined Computational Study
por: Liu, Jingli, et al.
Publicado: (2022)

Pharmacological Actions of Multi-Target-Directed Evodiamine
por: Yu, Hui, et al.
Publicado: (2013)

Antitumor activity of IL-32β through the activation of lymphocytes, and the inactivation of NF-κB and STAT3 signals
por: Yun, H-M, et al.
Publicado: (2013)

Improved absorption and in vivo kinetic characteristics of nanoemulsions containing evodiamine–phospholipid nanocomplex
por: Hu, Jiangbo, et al.
Publicado: (2014)

Antiproliferative Effects of Alkaloid Evodiamine and Its Derivatives
por: Hu, Xu, et al.
Publicado: (2018)

Sophocarpine Suppresses NF-κB-Mediated Inflammation Both In Vitro and In Vivo and Inhibits Diabetic Cardiomyopathy
por: Zou, Fang, et al.
Publicado: (2019)

Preventive Effects of Evodiamine on Dexamethasone-Induced Osteoporosis in Zebrafish
por: Yin, Heng, et al.
Publicado: (2019)

Utilizing the nanosecond pulse technique to improve antigen intracellular delivery and presentation to treat tongue squamous cell carcinoma
por: Gao, Cen, et al.
Publicado: (2018)

Preclinical in vivo Antitumor Efficacy of Nedaplatin with Gemcitabine against Human Lung Cancer
por: Matsumoto, Mitsunobu, et al.
Publicado: (2001)

Andrographolide Protects against LPS-Induced Acute Lung Injury by Inactivation of NF-κB
por: Zhu, Tao, et al.
Publicado: (2013)

Involvement of Akt/NF-κB pathway in antitumor effects of parthenolide on glioblastoma cells in vitro and in vivo
por: Nakabayashi, Hiromichi, et al.
Publicado: (2012)

Enhanced transdermal delivery of evodiamine and rutaecarpine using microemulsion
por: Zhang, Yong-Tai, et al.
Publicado: (2011)

NF-κB inducing kinase maintains T cell metabolic fitness in antitumor immunity
por: Gu, Meidi, et al.
Publicado: (2021)

Preparation of Evodiamine Solid Dispersions and Its Pharmacokinetics
por: Xu, H., et al.
Publicado: (2011)

Pharmacological Basis for the Use of Evodiamine in Alzheimer’s Disease: Antioxidation and Antiapoptosis
por: Zhang, Yongfeng, et al.
Publicado: (2018)

Anti-Proliferative Effects of Evodiamine on Human Breast Cancer Cells
por: Wang, Kai-Lee, et al.
Publicado: (2013)

Paeoniflorin regulates osteoclastogenesis and osteoblastogenesis via manipulating NF-κB signaling pathway both in vitro and in vivo
por: Wang, Yanmao, et al.
Publicado: (2017)

Evodiamine, a Novel NOTCH3 Methylation Stimulator, Significantly Suppresses Lung Carcinogenesis in Vitro and in Vivo
por: Su, Tao, et al.
Publicado: (2018)

Evodiamine-inspired dual inhibitors of histone deacetylase 1 (HDAC1) and topoisomerase 2 (TOP2) with potent antitumor activity
por: Huang, Yahui, et al.
Publicado: (2020)

Pomalidomide enhanced gemcitabine and nab-paclitaxel on pancreatic cancer both in vitro and in vivo
por: Saito, Nobuhiro, et al.
Publicado: (2018)

AduPARE1A and gemcitabine combined treatment trigger synergistic antitumor effects in pancreatic cancer through NF-κB mediated uPAR activation
por: Maliandi, Maria Victoria, et al.
Publicado: (2015)

In vitro cellular uptake of evodiamine and rutaecarpine using a microemulsion
por: Zhang, Yong-Tai, et al.
Publicado: (2012)

OXCT1 Enhances Gemcitabine Resistance Through NF-κB Pathway in Pancreatic Ductal Adenocarcinoma
por: Ding, Jinsheng, et al.
Publicado: (2021)

A Critical YAP in Malignancy of HCC Is Regulated by Evodiamine
por: Yun, Un-Jung, et al.
Publicado: (2022)

Neuroprotective Studies of Evodiamine in an Okadaic Acid-Induced Neurotoxicity
por: Chou, Ching-Hsuan, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_3npui0td7s4bp5rjqp8tsqmn0e