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An Explant Technique for High-Resolution Imaging and Manipulation of Mycobacterial Granulomas
A central and critical structure in tuberculosis, the mycobacterial granuloma consists of highly organized immune cells, including macrophages that drive granuloma formation through a characteristic epithelioid transformation. Difficulties in imaging within intact animals as well as the inherent cav...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6312189/ https://www.ncbi.nlm.nih.gov/pubmed/30504889 http://dx.doi.org/10.1038/s41592-018-0215-8 |