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An Explant Technique for High-Resolution Imaging and Manipulation of Mycobacterial Granulomas

A central and critical structure in tuberculosis, the mycobacterial granuloma consists of highly organized immune cells, including macrophages that drive granuloma formation through a characteristic epithelioid transformation. Difficulties in imaging within intact animals as well as the inherent cav...

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Detalles Bibliográficos
Autores principales: Cronan, Mark R., Matty, Molly A., Rosenberg, Allison F., Blanc, Landry, Pyle, Charlie J., Espenschied, Scott T., Rawls, John F., Dartois, Véronique, Tobin, David M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6312189/
https://www.ncbi.nlm.nih.gov/pubmed/30504889
http://dx.doi.org/10.1038/s41592-018-0215-8