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Advances in functional genetic screening with transposons and CRISPR/Cas9 to illuminate cancer biology

Large-scale genome sequencing studies have identified a wealth of mutations in human tumors and have dramatically advanced the field of cancer genetics. However, the functional consequences of an altered gene in tumor progression cannot always be inferred from mutation status alone. This underscores...

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Detalles Bibliográficos
Autor principal: O’Donnell, Kathryn A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6312197/
https://www.ncbi.nlm.nih.gov/pubmed/29587177
http://dx.doi.org/10.1016/j.gde.2018.03.006