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Advances in functional genetic screening with transposons and CRISPR/Cas9 to illuminate cancer biology
Large-scale genome sequencing studies have identified a wealth of mutations in human tumors and have dramatically advanced the field of cancer genetics. However, the functional consequences of an altered gene in tumor progression cannot always be inferred from mutation status alone. This underscores...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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2018
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6312197/ https://www.ncbi.nlm.nih.gov/pubmed/29587177 http://dx.doi.org/10.1016/j.gde.2018.03.006 |