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Catalytic mechanism of the tyrosinase reaction toward the Tyr(98) residue in the caddie protein

Tyrosinase (EC 1.14.18.1), a copper-containing monooxygenase, catalyzes the conversion of phenol to the corresponding ortho-quinone. The Streptomyces tyrosinase is generated as a complex with a “caddie” protein that facilitates the transport of two copper ions into the active center. In our previous...

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Detalles Bibliográficos
Autores principales: Matoba, Yasuyuki, Kihara, Shogo, Bando, Naohiko, Yoshitsu, Hironari, Sakaguchi, Miyuki, Kayama, Kure’e, Yanagisawa, Sachiko, Ogura, Takashi, Sugiyama, Masanori
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6312201/
https://www.ncbi.nlm.nih.gov/pubmed/30596633
http://dx.doi.org/10.1371/journal.pbio.3000077