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Toll-like receptor 2 confers partial neuroprotection during prion disease

Neuroinflammation and neurodegeneration are common during prion infection, but the mechanisms that underlie these pathological features are not well understood. Several components of innate immunity, such as Toll-like receptor (TLR) 4 and Complement C1q, have been shown to influence prion disease. T...

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Detalles Bibliográficos
Autores principales: Carroll, James A., Race, Brent, Williams, Katie, Chesebro, Bruce
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6312208/
https://www.ncbi.nlm.nih.gov/pubmed/30596651
http://dx.doi.org/10.1371/journal.pone.0208559