Pharmacokinetic/pharmacodynamic (PK/PD) evaluation of tulathromycin against Haemophilus parasuis in an experimental neutropenic guinea pig model

The objective of the study was to develop an ex-vivo PK/PD model of intramuscular (IM) administration of tulathromycin and to test its efficacy against Haemophilus parasuis (H. parasuis) infection in intraperitoneal-inoculated neutropenic guinea pigs. The pharmacokinetics (PKs) of tulathromycin at d...

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Detalles Bibliográficos
Autores principales: Zhao, Yongda, Guo, Li-Li, Fang, Binghu, Liu, Baotao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6312216/
https://www.ncbi.nlm.nih.gov/pubmed/30596709
http://dx.doi.org/10.1371/journal.pone.0209177

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6312216/
https://www.ncbi.nlm.nih.gov/pubmed/30596709
http://dx.doi.org/10.1371/journal.pone.0209177

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