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Pharmacokinetic/pharmacodynamic (PK/PD) evaluation of tulathromycin against Haemophilus parasuis in an experimental neutropenic guinea pig model

The objective of the study was to develop an ex-vivo PK/PD model of intramuscular (IM) administration of tulathromycin and to test its efficacy against Haemophilus parasuis (H. parasuis) infection in intraperitoneal-inoculated neutropenic guinea pigs. The pharmacokinetics (PKs) of tulathromycin at d...

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Detalles Bibliográficos
Autores principales:	Zhao, Yongda, Guo, Li-Li, Fang, Binghu, Liu, Baotao
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2018
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6312216/ https://www.ncbi.nlm.nih.gov/pubmed/30596709 http://dx.doi.org/10.1371/journal.pone.0209177

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