A genetically engineered microRNA-34a prodrug demonstrates anti-tumor activity in a canine model of osteosarcoma

Osteosarcoma (OSA) represents the most common primary bone tumor in humans and pet dogs. Little progress has been made with regard to viable treatment options in the past three decades and patients presenting with metastatic disease continue to have a poor prognosis. Recent mouse studies have sugges...

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Detalles Bibliográficos
Autores principales: Alegre, Fernando, Ormonde, Amanda R., Snider, Kellie M., Woolard, Kevin, Yu, Ai-Ming, Wittenburg, Luke A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6312226/
https://www.ncbi.nlm.nih.gov/pubmed/30596759
http://dx.doi.org/10.1371/journal.pone.0209941

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6312226/
https://www.ncbi.nlm.nih.gov/pubmed/30596759
http://dx.doi.org/10.1371/journal.pone.0209941

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