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A genetically engineered microRNA-34a prodrug demonstrates anti-tumor activity in a canine model of osteosarcoma
Osteosarcoma (OSA) represents the most common primary bone tumor in humans and pet dogs. Little progress has been made with regard to viable treatment options in the past three decades and patients presenting with metastatic disease continue to have a poor prognosis. Recent mouse studies have sugges...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6312226/ https://www.ncbi.nlm.nih.gov/pubmed/30596759 http://dx.doi.org/10.1371/journal.pone.0209941 |