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Dynamic regulation of the Trypanosoma brucei transferrin receptor in response to iron starvation is mediated via the 3’UTR

The bloodstream form of the parasite Trypanosoma brucei obtains iron from its mammalian host by receptor-mediated endocytosis of host transferrin through its own unique transferrin receptor (TbTfR). Expression of TbTfR rapidly increases upon iron starvation by post-transcriptional regulation through...

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Detalles Bibliográficos
Autores principales: Benz, Corinna, Lo, Winston, Fathallah, Nadin, Connor-Guscott, Ashley, Benns, Henry J., Urbaniak, Michael D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6312234/
https://www.ncbi.nlm.nih.gov/pubmed/30596656
http://dx.doi.org/10.1371/journal.pone.0206332