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Dynamic regulation of the Trypanosoma brucei transferrin receptor in response to iron starvation is mediated via the 3’UTR
The bloodstream form of the parasite Trypanosoma brucei obtains iron from its mammalian host by receptor-mediated endocytosis of host transferrin through its own unique transferrin receptor (TbTfR). Expression of TbTfR rapidly increases upon iron starvation by post-transcriptional regulation through...
Autores principales: | Benz, Corinna, Lo, Winston, Fathallah, Nadin, Connor-Guscott, Ashley, Benns, Henry J., Urbaniak, Michael D. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6312234/ https://www.ncbi.nlm.nih.gov/pubmed/30596656 http://dx.doi.org/10.1371/journal.pone.0206332 |
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