In silico repositioning of approved drugs against Schistosoma mansoni energy metabolism targets

Schistosomiasis is a neglected parasitosis caused by Schistosoma spp. Praziquantel is used for the chemoprophylaxis and treatment of this disease. Although this monotherapy is effective, the risk of resistance and its low efficiency against immature worms compromises its effectiveness. Therefore, it...

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Detalles Bibliográficos
Autores principales: Calixto, Nicole Melo, dos Santos, Daniela Braz, Bezerra, José Clecildo Barreto, Silva, Lourival de Almeida
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6312253/
https://www.ncbi.nlm.nih.gov/pubmed/30596650
http://dx.doi.org/10.1371/journal.pone.0203340

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6312253/
https://www.ncbi.nlm.nih.gov/pubmed/30596650
http://dx.doi.org/10.1371/journal.pone.0203340

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