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Trichloroethene metabolite dichloroacetyl chloride induces apoptosis and compromises phagocytosis in Kupffer Cells: Activation of inflammasome and MAPKs

Exposure to trichloroethene (TCE), an occupational and ubiquitous environmental contaminant, is associated with the development of several autoimmune diseases, including autoimmune hepatitis (AIH). However, mechanisms contributing to TCE-mediated AIH are not known. Earlier, we have shown that dichlo...

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Detalles Bibliográficos
Autores principales: Wang, Hui, Wang, Gangduo, Ansari, G. A. Shakeel, Khan, M. Firoze
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6312261/
https://www.ncbi.nlm.nih.gov/pubmed/30596806
http://dx.doi.org/10.1371/journal.pone.0210200