Cargando…

Blockade of platelet-derived growth factor receptor-β, not receptor-α ameliorates bleomycin-induced pulmonary fibrosis in mice

Platelet-derived growth factor (PDGF) has been implicated in the pathogenesis of pulmonary fibrosis. Nintedanib, a multi-kinase inhibitor that targets several tyrosine kinases, including PDGF receptor (PDGFR), was recently approved as an anti-fibrotic agent to reduce the deterioration of FVC in pati...

Descripción completa

Detalles Bibliográficos
Autores principales:	Kishi, Masami, Aono, Yoshinori, Sato, Seidai, Koyama, Kazuya, Azuma, Momoyo, Abe, Shuichi, Kawano, Hiroshi, Kishi, Jun, Toyoda, Yuko, Okazaki, Hiroyasu, Ogawa, Hirohisa, Uehara, Hisanori, Nishioka, Yasuhiko
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2018
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6312310/ https://www.ncbi.nlm.nih.gov/pubmed/30596712 http://dx.doi.org/10.1371/journal.pone.0209786

Ejemplares similares

Anti-fibrotic efficacy of nintedanib in pulmonary fibrosis via the inhibition of fibrocyte activity
por: Sato, Seidai, et al.
Publicado: (2017)

IMD-4690, a Novel Specific Inhibitor for Plasminogen Activator Inhibitor-1, Reduces Allergic Airway Remodeling in a Mouse Model of Chronic Asthma via Regulating Angiogenesis and Remodeling-Related Mediators
por: Tezuka, Toshifumi, et al.
Publicado: (2015)

The lymphocyte-specific protein tyrosine kinase-specific inhibitor A-770041 attenuates lung fibrosis via the suppression of TGF-β production in regulatory T-cells
por: Kagawa, Kozo, et al.
Publicado: (2022)

Development of improved method to identify and analyze lung fibrocytes with flow cytometry in a reporter mouse strain
por: Kawano, Hiroshi, et al.
Publicado: (2020)

A polo-like kinase inhibitor identified by computational repositioning attenuates pulmonary fibrosis
por: Imakura, Takeshi, et al.
Publicado: (2023)

Lenvatinib-induced Interstitial Pneumonia in a Patient with Hepatocellular Carcinoma
por: Imakura, Takeshi, et al.
Publicado: (2021)

Brain Angiotensin II Type 1 Receptor Blockade Improves Dairy Blood Pressure Variability via Sympathoinhibition in Hypertensive Rats
por: Kishi, Takuya, et al.
Publicado: (2015)

Murine Typhus from Vietnam, Imported into Japan
por: Azuma, Momoyo, et al.
Publicado: (2006)

S‐1 eliminates MDSCs and enhances the efficacy of PD‐1 blockade via regulation of tumor‐derived Bv8 and S100A8 in thoracic tumor
por: Nguyen, Na T., et al.
Publicado: (2022)

Clinical Significance of Carbapenem-Tolerant Pseudomonas aeruginosa Isolated in the Respiratory Tract
por: Azuma, Momoyo, et al.
Publicado: (2020)

Richter’s Type of Incarcerated Obturator Hernia that Presented with a Deep Femoral Abscess: An Autopsy Case Report
por: Yonekura, Satoru, et al.
Publicado: (2016)

Surfactant protein D attenuates sub-epithelial fibrosis in allergic airways disease through TGF-β
por: Ogawa, Hirohisa, et al.
Publicado: (2014)

FoundationOne CDx detected an uncovered variant of epidermal growth factor receptor exon 19 deletion by Oncomine Dx target test in a patient with lung adenocarcinoma
por: Takahashi, Hiroki, et al.
Publicado: (2023)

Fibrocyte-like cells mediate acquired resistance to anti-angiogenic therapy with bevacizumab
por: Mitsuhashi, Atsushi, et al.
Publicado: (2015)

Multidisciplinary treatment of skeletal muscle metastasis from lung cancer: A case of triceps muscle metastasis of lung squamous cell cancer
por: Haji, Keiko, et al.
Publicado: (2021)

Immunohistochemical Detection of Propionibacterium acnes in Granulomas for Differentiating Sarcoidosis from Other Granulomatous Diseases Utilizing an Automated System with a Commercially Available PAB Antibody
por: Isshiki, Takuma, et al.
Publicado: (2021)

Association of rs3750920 polymorphism in TOLLIP with clinical characteristics of fibrosing interstitial lung diseases in Japanese
por: Isshiki, Takuma, et al.
Publicado: (2021)

Significance of the progesterone receptor and epidermal growth factor receptor, but not the estrogen receptor, in chemically induced lung carcinogenesis in female A/J mice
por: KISHI, SOSUKE, et al.
Publicado: (2014)

Induction of Apoptosis in Human Pancreatic Carcinoma Cells by a Synthetic Bleomycin‐like Ligand
por: Suginaka, Rei, et al.
Publicado: (1998)

Comprehensive and efficient analyses of T cell receptors for cancer antigens in peptide-vaccinated patients using a single cell-based gene cloning system
por: Nakagawa, Hidetoshi, et al.
Publicado: (2014)

Programmed death (PD)‐1/PD‐ligand 1 blockade mediates antiangiogenic effects by tumor‐derived CXCL10/11 as a potential predictive biomarker
por: Mitsuhashi, Atsushi, et al.
Publicado: (2021)

An Autopsy Case of Aortic Intimal Sarcoma Initially Diagnosed as Polyarteritis Nodosa
por: Toyoda, Yuko, et al.
Publicado: (2016)

NMDA Receptor Antagonist Attenuates Bleomycin-Induced Acute Lung Injury
por: Li, Yang, et al.
Publicado: (2015)

Analysis of the chemotactic factors for tumor-infiltrating fibrocytes and their prognostic significances in lung cancer
por: Tobiume, Makoto, et al.
Publicado: (2022)

Mineralocorticoid receptor blockade for renoprotection
por: Cha, Dae Ryong
Publicado: (2018)

Expression of the gonadotropin receptors during follicular development
por: Kishi, Hiroshi, et al.
Publicado: (2017)

Human Olfactory Receptor Sensor for Odor Reconstitution
por: Kuroda, Shun’ichi, et al.
Publicado: (2023)

Alteration of Interleukin 4 Production Results in the Inhibition of T Helper Type 2 Cell–Dominated Inflammatory Bowel Disease in T Cell Receptor α Chain–Deficient Mice
por: Iijima, Hideki, et al.
Publicado: (1999)

Systemic Sarcoidosis Presenting with Renal Involvement Caused by Various Sarcoidosis-associated Pathophysiological Conditions
por: Ueda, Sayo, et al.
Publicado: (2018)

Blockade of advanced glycation end product formation attenuates bleomycin-induced pulmonary fibrosis in rats
por: Chen, Lei, et al.
Publicado: (2009)

The IL-33 Receptor ST2 Regulates Pulmonary Inflammation and Fibrosis to Bleomycin
por: Fanny, Manoussa, et al.
Publicado: (2018)

Blocking Toll-like receptor 9 attenuates bleomycin-induced pulmonary injury
por: Alzahrani, Badr, et al.
Publicado: (2022)

Identification of tumor-specific T cell receptors from primary tumor-infiltrating lymphocytes
por: Kishi, Hiroyuki, et al.
Publicado: (2015)

Evaluation of chimeric antigen receptor of humanized rabbit‐derived T cell receptor‐like antibody
por: Nakamura, Tomoko, et al.
Publicado: (2022)

Angiotensin-receptor blockade in acute stroke
por: Rajendran, Srijithesh P.
Publicado: (2011)

A Possible Advantage of Glucagon-Like Peptide 1 Receptor Agonist in Kidney Transplant Recipients With Type 2 Diabetes
por: Sato, Tetsuhiko, et al.
Publicado: (2021)

Early Deletion and Late Positive Selection of T-Cells Expressing a Male-Specific Receptor in T-Cell Receptor Transgenic Mice
por: Teh, Hung Sia, et al.
Publicado: (1990)

Modulation of Bleomycin-Induced Lung Fibrosis by Pegylated Hyaluronidase and Dopamine Receptor Antagonist in Mice
por: Skurikhin, Evgenii Germanovich, et al.
Publicado: (2015)

Toll-like receptor expression in pulmonary sensory neurons in the bleomycin-induced fibrosis model
por: Jung, Won Jai, et al.
Publicado: (2018)

Lack of bombesin receptor–activated protein attenuates bleomycin-induced pulmonary fibrosis in mice
por: Wang, Hui, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_oh9mujoa0q3l167md300mj5o07