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Hair pyrrole adducts serve as biomarkers for peripheral nerve impairment induced by 2,5-hexanedione and n-hexane in rats

Pyrrole adducts are specific reaction products of 2,5-hexadione (2,5-HD) in vivo and are considered highly relevant to the pathogenesis of peripheral nerve impairments after exposure to n-hexane, though the exact mechanism remains unclear. In this study, 40 male Wistar rats were randomly divided int...

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Detalles Bibliográficos
Autores principales: Li, Xianjie, Wang, Qiong, Li, Ming, Wang, Shuo, Zhang, Cuiqin, Xie, Keqin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6312332/
https://www.ncbi.nlm.nih.gov/pubmed/30596762
http://dx.doi.org/10.1371/journal.pone.0209939