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Myocardial Notch1-Rbpj deletion does not affect NOTCH signaling, heart development or function

During vertebrate cardiac development NOTCH signaling activity in the endocardium is essential for the crosstalk between endocardium and myocardium that initiates ventricular trabeculation and valve primordium formation. This crosstalk leads later to the maturation and compaction of the ventricular...

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Detalles Bibliográficos
Autores principales: Salguero-Jiménez, Alejandro, Grego-Bessa, Joaquim, D’Amato, Gaetano, Jiménez-Borreguero, Luis J., de la Pompa, José Luis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6312338/
https://www.ncbi.nlm.nih.gov/pubmed/30596653
http://dx.doi.org/10.1371/journal.pone.0203100