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Myocardial Notch1-Rbpj deletion does not affect NOTCH signaling, heart development or function
During vertebrate cardiac development NOTCH signaling activity in the endocardium is essential for the crosstalk between endocardium and myocardium that initiates ventricular trabeculation and valve primordium formation. This crosstalk leads later to the maturation and compaction of the ventricular...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6312338/ https://www.ncbi.nlm.nih.gov/pubmed/30596653 http://dx.doi.org/10.1371/journal.pone.0203100 |