Quantitative RNAseq analysis of Ugandan KS tumors reveals KSHV gene expression dominated by transcription from the LTd downstream latency promoter

KSHV is endemic in Uganda and the HIV epidemic has dramatically increased the incidence of Kaposi sarcoma (KS). To investigate the role of KSHV in the development of KS, we obtained KS biopsies from ART-naïve, HIV-positive individuals in Uganda and analyzed the tumors using RNAseq to globally charac...

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Detalles Bibliográficos
Autores principales: Rose, Timothy M., Bruce, A. Gregory, Barcy, Serge, Fitzgibbon, Matt, Matsumoto, Lisa R., Ikoma, Minako, Casper, Corey, Orem, Jackson, Phipps, Warren
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6312348/
https://www.ncbi.nlm.nih.gov/pubmed/30557332
http://dx.doi.org/10.1371/journal.ppat.1007441

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6312348/
https://www.ncbi.nlm.nih.gov/pubmed/30557332
http://dx.doi.org/10.1371/journal.ppat.1007441

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