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β-actin regulates a heterochromatin landscape essential for optimal induction of neuronal programs during direct reprograming

During neuronal development, β-actin serves an important role in growth cone mediated axon guidance. Consistent with this notion, in vivo ablation of the β-actin gene leads to abnormalities in the nervous system. However, whether β-actin is involved in the regulation of neuronal gene programs is not...

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Detalles Bibliográficos
Autores principales: Xie, Xin, Jankauskas, Robertas, Mazari, Aslam M. A., Drou, Nizar, Percipalle, Piergiorgio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6312353/
https://www.ncbi.nlm.nih.gov/pubmed/30557298
http://dx.doi.org/10.1371/journal.pgen.1007846