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Bayesian inference of protein conformational ensembles from limited structural data
Many proteins consist of folded domains connected by regions with higher flexibility. The details of the resulting conformational ensemble play a central role in controlling interactions between domains and with binding partners. Small-Angle Scattering (SAS) is well-suited to study the conformationa...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6312354/ https://www.ncbi.nlm.nih.gov/pubmed/30557358 http://dx.doi.org/10.1371/journal.pcbi.1006641 |