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Gluconeogenesis is essential for trypanosome development in the tsetse fly vector

In the glucose-free environment that is the midgut of the tsetse fly vector, the procyclic form of Trypanosoma brucei primarily uses proline to feed its central carbon and energy metabolism. In these conditions, the parasite needs to produce glucose 6-phosphate (G6P) through gluconeogenesis from met...

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Detalles Bibliográficos
Autores principales: Wargnies, Marion, Bertiaux, Eloïse, Cahoreau, Edern, Ziebart, Nicole, Crouzols, Aline, Morand, Pauline, Biran, Marc, Allmann, Stefan, Hubert, Jane, Villafraz, Oriana, Millerioux, Yoann, Plazolles, Nicolas, Asencio, Corinne, Rivière, Loïc, Rotureau, Brice, Boshart, Michael, Portais, Jean-Charles, Bringaud, Frédéric
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6312356/
https://www.ncbi.nlm.nih.gov/pubmed/30557412
http://dx.doi.org/10.1371/journal.ppat.1007502