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The Integrator complex regulates differential snRNA processing and fate of adult stem cells in the highly regenerative planarian Schmidtea mediterranea

In multicellular organisms, cell type diversity and fate depend on specific sets of transcript isoforms generated by post-transcriptional RNA processing. Here, we used Schmidtea mediterranea, a flatworm with extraordinary regenerative abilities and a large pool of adult stem cells, as an in vivo mod...

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Detalles Bibliográficos
Autores principales: Schmidt, David, Reuter, Hanna, Hüttner, Katja, Ruhe, Larissa, Rabert, Franziska, Seebeck, Florian, Irimia, Manuel, Solana, Jordi, Bartscherer, Kerstin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6312358/
https://www.ncbi.nlm.nih.gov/pubmed/30557303
http://dx.doi.org/10.1371/journal.pgen.1007828