SG formation relies on eIF4GI-G3BP interaction which is targeted by picornavirus stress antagonists

Typical stress granules (tSGs) are stalled translation pre-initiation complex aggregations in the cytoplasm, and their formation is a common consequence of translation initiation inhibition under stress. We previously found that 2A protease of picornaviruses blocks tSG formation and induces atypical...

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Detalles Bibliográficos
Autores principales: Yang, Xiaodan, Hu, Zhulong, Zhang, Qiang, Fan, Shanshan, Zhong, Yi, Guo, Dong, Qin, Yali, Chen, Mingzhou
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6312541/
https://www.ncbi.nlm.nih.gov/pubmed/30603102
http://dx.doi.org/10.1038/s41421-018-0068-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6312541/
https://www.ncbi.nlm.nih.gov/pubmed/30603102
http://dx.doi.org/10.1038/s41421-018-0068-4

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