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SG formation relies on eIF4GI-G3BP interaction which is targeted by picornavirus stress antagonists
Typical stress granules (tSGs) are stalled translation pre-initiation complex aggregations in the cytoplasm, and their formation is a common consequence of translation initiation inhibition under stress. We previously found that 2A protease of picornaviruses blocks tSG formation and induces atypical...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6312541/ https://www.ncbi.nlm.nih.gov/pubmed/30603102 http://dx.doi.org/10.1038/s41421-018-0068-4 |