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Targeting mTOR in Glioblastoma: Rationale and Preclinical/Clinical Evidence
The mechanistic target of rapamycin (mTOR) drives several physiologic and pathologic cellular processes and is frequently deregulated in different types of tumors, including glioblastoma (GBM). Despite recent advancements in understanding the molecular mechanisms involved in GBM biology, the surviva...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6312595/ https://www.ncbi.nlm.nih.gov/pubmed/30662577 http://dx.doi.org/10.1155/2018/9230479 |