Hexafluoroisopropanol-Mediated Domino Reaction for the Synthesis of Thiazolo-androstenones: Potent Anticancer Agents

[Image: see text] A cascade reaction of thioamides with 6β-bromoandrostenedione in hexafluoroisopropanol formed substituted thiazolo-androstenones. This is a simple and mild protocol to synthesize novel molecules by using readily available reagents and substrates. Feasibility of the reaction has bee...

Descripción completa

Detalles Bibliográficos
Autores principales: Okolo, ChrisTina, Ali, Mohamad Akbar, Newman, Matthew, Chambers, Steven A., Whitt, Jedidiah, Alsharif, Zakeyah A., Day, Victor W., Alam, Mohammad A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2018
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6312635/
https://www.ncbi.nlm.nih.gov/pubmed/30613817
http://dx.doi.org/10.1021/acsomega.8b02840

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6312635/
https://www.ncbi.nlm.nih.gov/pubmed/30613817
http://dx.doi.org/10.1021/acsomega.8b02840

Ejemplares similares