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Formulation and clinical investigation of optimized vinpocetine lyoplant-tabs: new strategy in development of buccal solid dosage form
BACKGROUND: This work aimed to develop a new solid dosage formulation of vinpocetine (VPN) in the form of buccal freeze-dried pullulan-based tablets (lyoplant-tabs) loaded with physically modified drug binary system. METHODS: Different polyvinyl pyrrolidone (PVP) grades were studied to prepare an ef...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Dove Medical Press
2018
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6312694/ https://www.ncbi.nlm.nih.gov/pubmed/30643387 http://dx.doi.org/10.2147/DDDT.S189105 |