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Recombined humanized endostatin‐induced suppression of HMGB1 expression inhibits proliferation of NSCLC cancer cells

BACKGROUND: Recombined humanized endostatin (Rh‐endostatin) exhibits a potent anti‐cancer effect involving multiple molecular targets and signaling pathways. HMGB1 is a highly conserved DNA‐binding protein involved in cancer development. The therapeutic effect of Rh‐endostatin on HMGB1 has not been...

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Detalles Bibliográficos
Autores principales: Meng, Fan‐Jie, Wang, Shuo, Yan, Yi‐Jie, Wang, Chun‐Yang, Guan, Zhi‐Yu, Zhang, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons Australia, Ltd 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6312838/
https://www.ncbi.nlm.nih.gov/pubmed/30485686
http://dx.doi.org/10.1111/1759-7714.12905