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Transient temperature fluctuations severely decrease P. falciparum susceptibility to artemisinin in vitro

Clinical studies suggest that outcomes for hospitalised malaria patients can be improved by managed hypothermia during treatment. We examined the impact of short pulses of low temperature on ring-stage susceptibility of Plasmodium falciparum to artemisinin in vitro. The usually artemisinin-sensitive...

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Detalles Bibliográficos
Autores principales: Henrici, Ryan C., van Schalkwyk, Donelly A., Sutherland, Colin J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6312858/
https://www.ncbi.nlm.nih.gov/pubmed/30599390
http://dx.doi.org/10.1016/j.ijpddr.2018.12.003