Cargando…
Chemical genetic identification of GAK substrates reveals its role in regulating Na(+)/K(+)-ATPase
Cyclin G–associated kinase (GAK) is a ubiquitous serine/threonine kinase that facilitates clathrin uncoating during vesicle trafficking. GAK phosphorylates a coat adaptor component, AP2M1, to help achieve this function. GAK is also implicated in Parkinson's disease through genome-wide associati...
Autores principales: | , , , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Life Science Alliance LLC
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6312924/ https://www.ncbi.nlm.nih.gov/pubmed/30623173 http://dx.doi.org/10.26508/lsa.201800118 |