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Deubiquitinating enzyme 4 facilitates chemoresistance in glioblastoma by inhibiting P53 activity
Glioblastoma is a malignant primary brain tumor with poor prognosis with a median survival of only 12–15 months. The high mortality rate of this disease is mainly due to the chemoresistance resulting from various reasons. Ubiquitin-specific protease 4 (USP4) has recently been found to be elevated in...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
D.A. Spandidos
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6312926/ https://www.ncbi.nlm.nih.gov/pubmed/30655854 http://dx.doi.org/10.3892/ol.2018.9654 |