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Bone mesenchymal stromal cells exhibit functional inhibition but no chromosomal aberrations in chronic myelogenous leukemia

Chronic myelogenous leukemia (CML) is a myeloproliferative neoplasia characterized by the presence of the Philadelphia (Ph) chromosome in hematopoietic cells (HCs). As one of the most important components of the bone marrow microenvironment (BMM), bone mesenchymal stromal cells (BMSCs) are critical...

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Detalles Bibliográficos
Autores principales: Xie, Jieqiong, Chen, Jiadi, Wang, Bin, He, Xuchun, Huang, Huifang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6312938/
https://www.ncbi.nlm.nih.gov/pubmed/30655859
http://dx.doi.org/10.3892/ol.2018.9681