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p53-independent role of MYC mutant T58A in the proliferation and apoptosis of breast cancer cells

Myc proto-oncogene (MYC) is an oncoprotein that promotes proliferation and apoptosis. MYC mutations frequently disrupt the apoptotic processes during tumorigenesis. In the present study, the effects of the MYC point mutation T58A on the progression of a cellular tumor antigen p53 (p53)(−/−) human br...

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Detalles Bibliográficos
Autores principales: Jiang, Dandan, Song, Yuhua, Cao, Weihong, Wang, Xingang, Jiang, Danni, Lv, Zhidong, Yang, Zhaochuan, Li, Funian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6312996/
https://www.ncbi.nlm.nih.gov/pubmed/30655867
http://dx.doi.org/10.3892/ol.2018.9688