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Curcumin-induced promoter hypermethylation of the mammalian target of rapamycin gene in multiple myeloma cells

Curcumin, a polyphenol derived from the rhizome of Curcuma, is a potential tumor inhibitor through affecting signaling pathways and epigenetic regulation. The mammalian target of rapamycin (mTOR) gene serves a crucial role in the carcinogenesis of multiple myeloma. The curcumin-induced epigenetic re...

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Detalles Bibliográficos
Autores principales: Chen, Jiaqi, Ying, Yongli, Zhu, Hongjun, Zhu, Tingjun, Qu, Chunsheng, Jiang, Jinhong, Fang, Bingmu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6312997/
https://www.ncbi.nlm.nih.gov/pubmed/30655872
http://dx.doi.org/10.3892/ol.2018.9662