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Inhibition of autophagy enhances adenosine-induced apoptosis in human hepatoblastoma HepG2 cells

In cancer research, autophagy acts as a double-edged sword: It increases cell viability or induces cell apoptosis depending upon the cell context and functional status. Recent studies have shown that adenosine (Ado) has cytotoxic effects in many tumors. However, the role of autophagy in Ado-induced...

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Detalles Bibliográficos
Autores principales: Zhou, Xiao-Tao, Pu, Ze-Jin, Liu, Li-Xuan, Li, Guo-Ping, Feng, Jia-Lin, Zhu, Hua-Chen, Wu, Ling-Fei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6313051/
https://www.ncbi.nlm.nih.gov/pubmed/30535464
http://dx.doi.org/10.3892/or.2018.6899