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Gadofosveset-enhanced MRI as simple surrogate parameter for real-time evaluation of the initial tumour vessel infarction by retargeted tissue factor tTF-NGR

Truncated tissue factor (tTF)-NGR consists of the extracellular domain of the human TF and the binding motif NGR. tTF-NGR activates blood coagulation within the tumour vasculature following binding to CD13, and is overexpressed in the endothelial cells of tumour vessels, resulting in tumour vessel i...

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Detalles Bibliográficos
Autores principales: Höink, Anna, Persigehl, Thorsten, Kwiecien, Robert, Balthasar, Martin, Mesters, Rolf, Berdel, Wolfgang, Heindel, Walter, Bremer, Christoph, Schwöppe, Christian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6313167/
https://www.ncbi.nlm.nih.gov/pubmed/30655764
http://dx.doi.org/10.3892/ol.2018.9638