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Gadofosveset-enhanced MRI as simple surrogate parameter for real-time evaluation of the initial tumour vessel infarction by retargeted tissue factor tTF-NGR
Truncated tissue factor (tTF)-NGR consists of the extracellular domain of the human TF and the binding motif NGR. tTF-NGR activates blood coagulation within the tumour vasculature following binding to CD13, and is overexpressed in the endothelial cells of tumour vessels, resulting in tumour vessel i...
Autores principales: | Höink, Anna, Persigehl, Thorsten, Kwiecien, Robert, Balthasar, Martin, Mesters, Rolf, Berdel, Wolfgang, Heindel, Walter, Bremer, Christoph, Schwöppe, Christian |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
D.A. Spandidos
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6313167/ https://www.ncbi.nlm.nih.gov/pubmed/30655764 http://dx.doi.org/10.3892/ol.2018.9638 |
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