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Patient-derived xenograft mouse models: A high fidelity tool for individualized medicine

Patient-derived xenograft (PDX) mouse models involve the direct transfer of fresh human tumor samples into immunodeficient mice following surgical resection or other medical operations. Gene expression in tumors may be maintained by serial passages of tumors from mouse to mouse. These models aid res...

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Detalles Bibliográficos
Autores principales: Xu, Cong, Li, Xuelu, Liu, Pixu, Li, Man, Luo, Fuwen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6313209/
https://www.ncbi.nlm.nih.gov/pubmed/30655732
http://dx.doi.org/10.3892/ol.2018.9583