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Enzymes Catalyzing the TCA- and Urea Cycle Influence the Matrix Composition of Biofilms Formed by Methicillin-Resistant Staphylococcus aureus USA300

In methicillin-sensitive Staphylococcus aureus (MSSA), the tricarboxylic acid (TCA) cycle is known to negatively regulate production of the major biofilm-matrix exopolysaccharide, PIA/PNAG. However, methicillin-resistant S. aureus (MRSA) produce a primarily proteinaceous biofilm matrix, and contribu...

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Detalles Bibliográficos
Autores principales: De Backer, Sarah, Sabirova, Julia, De Pauw, Ines, De Greve, Henri, Hernalsteens, Jean-Pierre, Goossens, Herman, Malhotra-Kumar, Surbhi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6313315/
https://www.ncbi.nlm.nih.gov/pubmed/30380651
http://dx.doi.org/10.3390/microorganisms6040113