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Enzymes Catalyzing the TCA- and Urea Cycle Influence the Matrix Composition of Biofilms Formed by Methicillin-Resistant Staphylococcus aureus USA300
In methicillin-sensitive Staphylococcus aureus (MSSA), the tricarboxylic acid (TCA) cycle is known to negatively regulate production of the major biofilm-matrix exopolysaccharide, PIA/PNAG. However, methicillin-resistant S. aureus (MRSA) produce a primarily proteinaceous biofilm matrix, and contribu...
Autores principales: | De Backer, Sarah, Sabirova, Julia, De Pauw, Ines, De Greve, Henri, Hernalsteens, Jean-Pierre, Goossens, Herman, Malhotra-Kumar, Surbhi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6313315/ https://www.ncbi.nlm.nih.gov/pubmed/30380651 http://dx.doi.org/10.3390/microorganisms6040113 |
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