Persistent Overexposure to N-Methyl-d-Aspartate (NMDA) Calcium-Dependently Downregulates Glutamine Synthetase, Aquaporin 4, and Kir4.1 Channel in Mouse Cortical Astrocytes

Astrocytes express N-methyl-d-aspartate (NMDA) receptor (NMDAR) but its functions in these cells are not well defined. This study shows that the sustained exposure (8–72 h) of mouse astrocytes to NMDA decreases the expression of the functional astroglia-specific proteins, glutamine synthetase (GS),...

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Detalles Bibliográficos
Autores principales: Skowrońska, Katarzyna, Obara-Michlewska, Marta, Czarnecka, Anna, Dąbrowska, Katarzyna, Zielińska, Magdalena, Albrecht, Jan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2018
Materias:
Short Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6313349/
https://www.ncbi.nlm.nih.gov/pubmed/30220059
http://dx.doi.org/10.1007/s12640-018-9958-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6313349/
https://www.ncbi.nlm.nih.gov/pubmed/30220059
http://dx.doi.org/10.1007/s12640-018-9958-3

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