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Low-Dose Naltrexone (LDN)—Review of Therapeutic Utilization

Naltrexone and naloxone are classical opioid antagonists. In substantially lower than standard doses, they exert different pharmacodynamics. Low-dose naltrexone (LDN), considered in a daily dose of 1 to 5 mg, has been shown to reduce glial inflammatory response by modulating Toll-like receptor 4 sig...

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Detalles Bibliográficos
Autores principales: Toljan, Karlo, Vrooman, Bruce
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6313374/
https://www.ncbi.nlm.nih.gov/pubmed/30248938
http://dx.doi.org/10.3390/medsci6040082